D-Glucarate is a phytochemical found in such fruits and vegetables as orange pith and broccoli. D-Glucarate inhibits an enzyme known as beta-glucuronidase, which suppresses the body's ability to detoxify many toxins using the glucuronidation pathway. Research supports a role for glucuronidation in protecting cells (especially those of hormone-sensitive tissues such as the breast and prostate) from dangerous environmental chemicals.